RAF Typhoon FGR4s have conducted a mission with France's air force in a joint strike against an hidden munitions depot in Syrian territory employed by the IS group, as stated by the UK Ministry of Defence.
The facility, pinpointed through intelligence, was thought to be containing munitions and bombs, the statement said, and was positioned in hills just above the ancient city of Palmyra in Syria's central region.
"Our fighter planes utilized laser-guided Paveway IV weapons to target a several access tunnels down to the depot... initial indications suggest the strike was effective," the MoD said.
There was no indication of any civilian casualties in the attack late on Saturday and all the aircraft made a safe return, the MoD added.
The Typhoon FGR4s were supported by a Voyager tanker plane.
Daesh - referred to as the so-called Islamic State - enforced militant control over parts of Iraq and Syria before its territorial defeat in 2019.
"This action shows our UK leadership, and resolve to operate in unison with our partners, to stamp out any resurgence of Daesh and their dangerous and violent ideologies in the Middle East," the British Defence Secretary the minister stated.
RAF aircraft have conducted overwatch operations over Syrian airspace to "deter any efforts to regroup" of IS after its defeat at the Baghuz confrontation in the year 2019, the authorities noted.
"I must thank every member of the UK armed forces participating in this operation for their expertise and their courage," he added. "They were part of thousands of UK service members on duty over the festive period. This mission, to eliminate dangerous terrorists who threaten our way of life, demonstrates how our armed forces are ready to step up, continuously, ensuring Britain's security within its borders and strong abroad."
In December, the American forces conducted what it described as a "major assault" against Islamic State objectives in the country, subsequent to an assault killed two US troops and a local interpreter in the Palmyra area.
The U.N. reports Islamic State still has an estimated 5,000 to 7,000 fighters in Syria and Iraq.